A direct, concise and stereoselective formal synthesis of platensimycin
| Title: | A direct, concise and stereoselective formal synthesis of platensimycin |
| Author: | Rivera, Heriberto |
| Abstract: | Herein we describe the synthesis of (±) platensimycin, a potent antibiotic against gram-positive bacteria. The first chapter reviews (±) platensimycin’s isolation, biological profile and previously reported studies relevant to the area. The second chapter describes our initial efforts to synthesize (±) platensimycin. The third chapter accounts our second generation synthesis and its completion. The fourth chapter entails the experimental details of the important compounds in our synthesis. |
| Department: | Chemistry |
| Subject: |
Platensimycin
Synthesis Antibiotic |
| URI: | http://hdl.handle.net/2152/ETD-UT-2011-12-4421 |
| Date: | 2011-12 |
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