A direct, concise and stereoselective formal synthesis of platensimycin

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A direct, concise and stereoselective formal synthesis of platensimycin

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Title: A direct, concise and stereoselective formal synthesis of platensimycin
Author: Rivera, Heriberto
Abstract: Herein we describe the synthesis of (±) platensimycin, a potent antibiotic against gram-positive bacteria. The first chapter reviews (±) platensimycin’s isolation, biological profile and previously reported studies relevant to the area. The second chapter describes our initial efforts to synthesize (±) platensimycin. The third chapter accounts our second generation synthesis and its completion. The fourth chapter entails the experimental details of the important compounds in our synthesis.
Department: Chemistry
Subject: Platensimycin Synthesis Antibiotic
URI: http://hdl.handle.net/2152/ETD-UT-2011-12-4421
Date: 2011-12

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